Sharjah

MITChemistry5.07

Biological Chemistry I

planned·~168 hours total

Professors

  • JoAnne Stubbe
  • John Essigmann

Textbook

  • Lehninger Principles of Biochemistry

    David L. Nelson, Michael M. Cox · 8th · ISBN 9781319228002

Prerequisites

Materials

Stubbe's biochemistry. Amino acids and protein structure through to enzyme mechanism, glycolysis, the citric acid cycle, oxidative phosphorylation. Lehninger is the standard text.

Syllabus

  1. Week 1

    Amino acids; peptide bonds

  2. Week 2

    Protein structure — primary through quaternary

  3. Week 3

    Protein folding; chaperones

  4. Week 4

    Enzyme catalysis; Michaelis-Menten kinetics

  5. Week 5

    Enzyme regulation; allostery

  6. Week 6

    Carbohydrates and glycolysis

  7. Week 7

    Citric acid cycle

  8. Week 8

    Oxidative phosphorylation; ATP synthesis

  9. Week 9

    Photosynthesis

  10. Week 10

    Lipid metabolism

  11. Week 11

    Amino acid and nucleotide metabolism

  12. Week 12

    Integration of metabolism; hormonal regulation