husayn gokal
Sharjah

MITEECS / Biology6.047

Computational Biology

planned·~168 hours total

Professor

  • Manolis Kellis
0

Prerequisites

Materials

Kellis's computational biology course — sequence alignment, hidden Markov models, phylogenetics, gene regulation, networks, evolutionary genomics.

Syllabus

  1. Week 1

    Genome alignment — dynamic programming

  2. Week 2

    BLAST and database search

  3. Week 3

    Hidden Markov models for gene finding

  4. Week 4

    Phylogenetic trees and inference

  5. Week 5

    Gene expression — clustering and classification

  6. Week 6

    Motif discovery; regulatory networks

  7. Week 7

    ChIP-seq; epigenomics

  8. Week 8

    Population genomics; GWAS

  9. Week 9

    Comparative genomics across species

  10. Week 10

    Cancer genomics; somatic mutations

  11. Week 11

    Networks; pathway analysis

  12. Week 12

    Deep learning in genomics